Basic Genomics Image Gallery

Title :

Cutting DNA with Restriction Enzymes

Description :

Isolated from various bacteria, restriction enzymes serve as microscopic scalpels that cut DNA molecules at specific sites. The enzyme EcoRI, for example, cuts double-stranded DNA only where it finds the sequence GAATTC. The resulting fragments can then be separated by gel electrophoresis. The electrophoresis pattern itself can be of interest, since variations in the pattern from a given chromosomal region can sometimes be associated with variations in genetic traits, including susceptibilities to certain diseases. Knowledge of the cutting sites also yields a kind of physical map known as a restriction map.

Citation :

1996 To Know Ourselves, The U.S. Department of Energy and the Human Genome Project.

Credit or Source :

Genome Management Information System, Oak Ridge National Laboratory

Hi Res :

No High-Resolution Image Available

Image Use and Credits
Almost all the images on these pages are original graphics created by the U.S. Department of Energy Genome Program's Genome Management Information System (GMIS). You will recognize GMIS images by their credit line. Permission to use these graphics is not needed, but please credit the U.S. Department of Energy Genome Programs and provide the website http://genomics.energy.gov. All other images were provided by third parties and not created by the U.S. Department of Energy. You must contact the person listed in the credit line before using those images.