Basic Genomics Image Gallery

Title :

Construction of an Overlapping Clone Library

Description :

A collection of clones of chromosomal DNA, called a library, has no obvious order indicating the original positions of the cloned pieces on the uncut chromosome. To establish that two particular clones are adjacent to each other in the genome, libraries of clones containing partly overlapping regions must be constructed. These clone libraries are ordered by dividing the inserts into smaller fragments and determining which clones share common DNA sequences.

Citation :

1992 U.S. DOE Primer on Molecular Genetics.

Credit or Source :

Genome Management Information System, Oak Ridge National Laboratory

Hi Res :

High-Resolution Image

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